Patent · US Active

Methods of treating cardiovascular disease with an anti-ASGR antibody or binding fragments thereof

US11066472B2 · kind B2 · utility

2Cited by
75References
47Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 21, 2018
Grant dateJul 20, 2021
Priority date
Expiry dateMay 26, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Antigen binding proteins that interact with ASGR, ASGR-1 and/or ASGR-2 are described as well as methods of making and using such antigen binding proteins. Methods of treating and preventing cardiovascular disease by administering a pharmaceutically effective amount of ASGR, ASGR-1 and/or ASGR-2 antigen binding proteins. Methods of treating and preventing cardiovascular disease by administering a pharmaceutically effective amount of interfering RNA compositions that reduce expression of ASGR, ASGR-1 and/or ASGR-2 are described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.