Bio-detection chip and detection method associated therewith
US11067570B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 23, 2018 |
| Grant date | Jul 20, 2021 |
| Priority date | — |
| Expiry date | Apr 19, 2039 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0415
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present disclosure relates to a bio-detection chip and a detection method associated therewith. The bio-detection chip includes an upper substrate, a lower substrate, a reference electrode, a driving electrode, and a first dielectric layer, a first hydrophobic layer, a second hydrophobic layer and a second dielectric layer disposed successively between the reference electrode and the driving electrode. The bio-detection chip further includes a plurality of micro-capsules arranged between the first hydrophobic layer and the second hydrophobic layer. Each micro-capsule encapsulates a plurality of charged microspheres, and surfaces of the charged microspheres have a first biomolecule for specifically binding with a second biomolecule that enters the bio-detection chip so as to give rise to a color change. The charged microspheres move close to the upper substrate when a voltage is applied between the reference electrode and the driving electrode. As such, a result of biomolecule detection may be observed intuitively.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.