Patent · US Active

Ethynyl compounds, their preparation and their therapeutic use for the treatment of malaria

US11078160B2 · kind B2 · utility

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15Claims
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Assignee

Inventors

Key dates

Filing dateJul 4, 2018
Grant dateAug 3, 2021
Priority date
Expiry dateAug 4, 2038

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present disclosure relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof wherein R1 means a fluorine atom or a perhalogeno linear alkyl radical containing 1, 2 or 3 carbon atoms; R2 means a chlorine atom, a linear alkyl radical containing 1, 2 or 3 carbon atoms or a perhalogeno linear alkyl radical containing 1, 2 or 3 carbon atoms, and R means a hydrogen atom or a radical of formula (Ia). The present disclosure also relates to processes for their preparation as well their therapeutic uses, in particular such as for use in the treatment of malaria.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.