Ca2+ regulated binding agents
US11078255B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Aug 26, 2019 |
| Grant date | Aug 3, 2021 |
| Priority date | — |
| Expiry date | Aug 26, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/49
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are binding agents that include (a) a calcium binding portion which includes an F-helix peptide and a calcium binding loop peptide derived from an EF-hand motif of a calcium binding protein, wherein the C-terminus of the F-helix peptide is covalently linked to the N-terminus of the calcium binding loop peptide by a peptide bond, and (b) a targeting peptide, wherein the N-terminus of the targeting peptide is covalently linked to the C-terminus of the calcium binding portion by a peptide bond. The binding agents can be used for diagnosis and treatment of various disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.