Patent · US Active

Ketoreductase polypeptides for the production of azetidinone

US11078466B2 · kind B2 · utility

1Cited by

36References

15Claims

0Family size

Assignee

Codexis, Inc. · US

Inventors

Onorato Campopiano · Hayward, US
Emily Mundorff · Garden City, US
Birthe Borup · Wesel, DE
Rama Voladri · Milpitas, US

Key dates

Filing date	Feb 13, 2020
Grant date	Aug 3, 2021
Priority date	—
Expiry date	Feb 13, 2040

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/52
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.