Patent · US Active

Deepsimulator method and system for mimicking nanopore sequencing

US11078531B2 · kind B2 · utility

1Cited by

0References

18Claims

0Family size

Assignee

King Abdullah University of Science and Technology · SA

Inventors

Xin Gao · Chengdu, CN
Yu-Lin Li · Apia, WS
Sheng Wang · Beijing, CN
Renmin HAN · Thuwal, SA

Key dates

Filing date	Oct 30, 2018
Grant date	Aug 3, 2021
Priority date	—
Expiry date	Oct 30, 2038

Classification

Technology area (CPC G)Physics
CPC primaryG16B40/30
WIPO fieldComputer technology
WIPO sectorElectrical engineering

Abstract

A method for sequencing biopolymers. The method includes selecting with a sequence generator module an input nucleotide sequence having plural k-mers; simulating with a deep learning simulator, actual electrical current signals corresponding to the input nucleotide sequence; identifying reads that correspond to the actual electrical current signals; and displaying the reads. The deep learning simulator includes a context-dependent deep learning model that takes into consideration a position of a k-mer of the plural k-mers on the input nucleotide sequence when calculating a corresponding actual electrical current.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.