Systems, methods, and media for de novo assembly of whole genome sequence data
US11081208B2 · kind B2 · utility
1Cited by
172References
29Claims
0Family size
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Key dates
| Filing date | Aug 19, 2016 |
| Grant date | Aug 3, 2021 |
| Priority date | — |
| Expiry date | Mar 2, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B30/10
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Described are computer-implemented methods, systems, and media for de novo phased diploid assembly of nucleic acid sequence data generated from a nucleic acid sample of an individual utilizing nucleic acid tags to preserve long-range sequence context for the individual such that a subset of short-read sequence data derived from a common starting sequence shares a common tag. The phased diploid assembly is achieved without alignment to a reference sequence derived from organisms other than the individual. The methods, systems, and media described are computer-resource efficient, allowing scale-up.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.