System and method for biological treatment planning and decision support

US11090508B2 · kind B2 · utility

Assignees

• VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH & CO. KG · DE
• VARIAN MEDICAL SYSTEMS INTERNATIONAL AG · CH
• VARIAN MEDICAL SYSTEMS, INC. · US

Inventors

• Michael Folkerts · Carrollton, US
• Jessica PEREZ · Geneva, CH
• Christel Smith · Midland School, US
• Eric Abel · San Jose, US
• Anthony Magliari · Newark, US
• Reynald Vanderstraeten · Uccle - Ukkel, BE
• Timo Koponen · Espoo, FI
• Renate Parry · Oakland, US
• Alexander Katsis · San Mateo, US
• Rajiv Dua · Manteca, US
• Michiko ALCANZARE · Espoo, FI
• Perttu Niemela · Espoo, FI
• Matti Ropo · Helsinki, FI

Key dates

• Filing date: Mar 8, 2019
• Grant date: Aug 17, 2021
• Expiry date: Aug 2, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N2005/1074
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Embodiments of the present invention provide an integrated solution to radiotherapy treatment planning that enables accurate recording and accumulation of physical parameters as input (e.g., dose, dose rate, irradiation time per voxel, etc.). User-defined functions are evaluated to correlate the input parameters with 4D biological outcomes. The resulting biological parameters can be visualized as a biological outcome map to evaluate decisions, support decisions, and optimize decisions regarding the parameters of the radiotherapy treatment plan, for example, for supporting clinical trials and related clinical research.