Patent · US Active

T cell which co-expresses a CD19 chimeric antigen receptor and a CD22 chimeric antigen receptor

US11091532B2 · kind B2 · utility

4Cited by

4References

16Claims

0Family size

Assignee

AUTOLUS LIMITED · GB

Inventors

Martin Pulé · London, GB
Shaun Cordoba · London, GB
Shimobi Onuoha · London, GB
Simon Thomas · London, GB

Key dates

Filing date	Dec 23, 2015
Grant date	Aug 17, 2021
Priority date	—
Expiry date	Dec 23, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2510/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a cell which co-expresses a first chimeric antigen receptor (CAR) and second CAR at the cell surface, each CAR comprising an antigen-binding domain, wherein the antigen-binding domain of the first CAR binds to CD19 and the antigen-binding domain of the second CAR binds to CD22.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.