Patent · US Active

Focal gene expression profiling of stained FFPE tissues with spatial correlation to morphology

US11091810B2 · kind B2 · utility

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6References
26Claims
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Key dates

Filing dateApr 16, 2018
Grant dateAug 17, 2021
Priority date
Expiry dateApr 16, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q2600/158
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Expression profiling of FFPE sample areas smaller than 2 mm2 with single-cell sensitivity, correlated with tissue microenvironment morphology and neoplastic grade. An automated digital molecular pathology instrument for integrated imaging, immunohistochemical assessment, and processing samples for sequence detection assays. Software for instrument and sample control and analysis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.