Patent · US Active

Systems for forming a nanopore in a membrane

US11092589B2 · kind B2 · utility

1Cited by
0References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 18, 2019
Grant dateAug 17, 2021
Priority date—
Expiry dateJul 18, 2039

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6869
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A method of forming a nanopore in a lipid bilayer is disclosed. A nanopore forming solution is deposited over a lipid bilayer. The nanopore forming solution has a concentration level and a corresponding activity level of pore molecules such that nanopores are substantially not formed un-stimulated in the lipid bilayer. Formation of a nanopore in the lipid bilayer is initiated by applying an agitation stimulus level to the lipid bilayer. In some embodiments, the concentration level and the corresponding activity level of pore molecules are at levels such that less than 30 percent of a plurality of available lipid bilayers have nanopores formed un-stimulated therein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.