Methods of identifying modulators of CASTOR1-GATOR2 interaction and use of same to modulate mTORC1
US11092608B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Dec 28, 2016 |
| Grant date | Aug 17, 2021 |
| Priority date | — |
| Expiry date | Dec 28, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/02
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to methods of identifying compounds that modulate mTORC1 activity in a cell by modulating the activity of CASTOR1, as well as to the use of such identified compounds in the modulation of mTORC1 and the treatment of diseases and conditions characterized by aberrant mTORC1 activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.