Lipids and complexes for the delivery of biologically-active material to cells
US11098006B2 · kind B2 · utility
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8References
13Claims
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Key dates
| Filing date | Mar 10, 2017 |
| Grant date | Aug 24, 2021 |
| Priority date | — |
| Expiry date | Sep 18, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A lipid comprising a tri-chain cation having a cationic head group and three or more C7-24 hydrocarbyl groups for use in non-viral gene delivery systems, for example in the formation of lipopolyplex transfection vectors. Exceptionally good nucleic acid transfection is observed when nucleic acid and targeting peptides are formulated with the lipid of the invention (or lipid formulated with a co-lipid) into a LPD complex.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.