Process for the preparation of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbontrile

US11098064B2 · kind B2 · utility

Assignees

• Loxo Oncology, Inc. · US
• Array BioPharma, Inc. · US

Inventors

• Charles Todd Eary · Stamford, US
• Stacey Spencer · Boulder, US
• Zack Crane · Longmont, US
• Katelyn Chando · Longmont, US
• Sylvie M. Asselin · Longmont, US
• Weidong Liu · Superior, US
• Mike Welch · Longmont, US
• Adam Cook · Boulder, US
• Gabrielle R. Kolakowski · Boulder, US
• Andrew T. Metcalf · Boulder, US
• David A. Moreno · Boulder, US
• Tony P. Tang · Boulder, US

Key dates

• Filing date: Jun 16, 2020
• Grant date: Aug 24, 2021
• Expiry date: Jun 16, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

In some embodiments, provided herein is a process for preparing a compound of Formula I or a pharmaceutically acceptable salt thereof, as disclosed herein.