Patent · US Active

Pegylated endostatin analogue and application thereof

US11098104B2 · kind B2 · utility

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0References

19Claims

0Family size

Assignee

BEIJING PROTGEN LTD. · CN

Inventors

Daifu Zhou · Beijing, CN
Wenchao Wang · Beijing, CN
Hui Li · Carlsbad, US
Guodong Chang · Beijing, CN

Key dates

Filing date	Nov 10, 2017
Grant date	Aug 24, 2021
Priority date	—
Expiry date	Nov 13, 2037

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a polyethylene glycol-modified endostatin analogue and an application thereof. The endostatin analogue is coupled to polyethylene glycol at lysine away from a nucleolin binding domain, or is coupled to polyethylene glycol at lysine away from a nucleolin binding domain and amidogen at the N end.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.