Combinatorial sets of nucleic acid barcodes for analysis of nucleic acids associated with single cells
US11098304B2 · kind B2 · utility
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40Claims
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Key dates
| Filing date | Nov 4, 2016 |
| Grant date | Aug 24, 2021 |
| Priority date | — |
| Expiry date | Nov 4, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6806
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are methods of identifying the origin of a nucleic acid sample. The methods include forming a reaction mixture comprising a nucleic acid sample comprising nucleic acid molecules from a single cell and a set of barcodes, incorporating the set of barcodes into the nucleic acid molecules of the sample, and identifying the set of barcodes incorporated into the nucleic acid molecules of the single cell thereby identifying the origin of the nucleic acid sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.