Compositions and methods for reactivating latent immunodeficiency virus

US11098309B2 · kind B2 · utility

Assignee

• The J. David Gladstone Institute, a testamentary trust established under the Will of J. David Gladstone · US

Inventors

• Melanie Ott · Mill Valley, US
• Daniela Boehm · San Francisco, US

Key dates

• Filing date: May 24, 2019
• Grant date: Aug 24, 2021
• Expiry date: May 24, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2310/531
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure provides compositions and methods for reactivating latent immunodeficiency virus and/or reducing transcription of HIV integrated into the genome of an HIV-infected cell. The present disclosure provides compositions and methods for treating an immunodeficiency virus infection.