Infectious disease vaccine using non-infectious paramyxovirus particle
US11103574B2 · kind B2 · utility
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Key dates
| Filing date | Nov 17, 2017 |
| Grant date | Aug 31, 2021 |
| Priority date | — |
| Expiry date | Feb 1, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/18843
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In this invention, a non-infectious particle has been produced, comprising a pathogen antigen protein caused to be expressed on the surface of a virus particle having at least one species of paramyxovirus envelope protein missing from the particle. This particle has been found to hold within the particle a large amount of antigen protein compared to an infectious particle, and to be capable of eliciting a host immune response with extremely high efficiency. The non-infectious particle according to the present invention is useful as a vaccine against a pathogenic virus, or the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.