Model based PBS optimization for flash therapy treatment planning and oncology information system

US11103727B2 · kind B2 · utility

Assignees

• VARIAN MEDICAL SYSTEMS INTERNATIONAL AG · CH
• VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH & CO. KG · DE
• VARIAN MEDICAL SYSTEMS, INC. · US

Inventors

• Michael Folkerts · Carrollton, US
• Jessica PEREZ · Geneva, CH
• Christel Smith · Midland School, US
• Eric Abel · San Jose, US
• Anthony Magliari · Newark, US
• Reynald Vanderstraeten · Uccle - Ukkel, BE
• Timo Koponen · Espoo, FI
• Renate Parry · Oakland, US
• Alexander Katsis · San Mateo, US
• Rajiv Dua · Manteca, US
• Michiko ALCANZARE · Espoo, FI
• Perttu Niemela · Espoo, FI
• Matti Ropo · Helsinki, FI

Key dates

• Filing date: Jun 11, 2019
• Grant date: Aug 31, 2021
• Expiry date: Aug 2, 2039

Classification

• Technology area (CPC G): Physics
• CPC primary: G06T2207/30004
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A computing system comprising a central processing unit (CPU), and memory coupled to the CPU and having stored therein instructions that, when executed by the computing system, cause the computing system to execute operations to generate a radiation treatment plan. The operations include accessing a minimum prescribed dose to be delivered into and across the target, determining a number of beams and directions of the beams, and determining a beam energy for each of the beams, wherein the number of beams, the directions of the beams, and the beam energy for each of the beams are determined such that the entire target receives the minimum prescribed dose. A quantitative time-dependent model-based charged particle pencil beam scanning optimization is then implemented for FLASH therapy.