Patent · US Active

Salts of TAM inhibitors

US11104682B2 · kind B2 · utility

7Cited by

8References

35Claims

0Family size

Assignee

Incyte Corporation · US

Inventors

Zhongjiang Jia · Kennett Square, US
Yongzhong Wu · Chadds Ford, US
Yongchun Pan · Wilmington, US
Jiacheng Zhou · Shanghai, CN
Qun Li · Beijing, CN

Key dates

Filing date	Mar 19, 2020
Grant date	Aug 31, 2021
Priority date	—
Expiry date	Mar 19, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/13
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present application provides salt forms of N-(4-(4-Amino-7-(1-isobutyrylpiperidin-4-yl)pyrrolo[1,2-f][1,2,4]triazin-5-yl)phenyl)-1-isopropyl-2,4-dioxo-3-(pyridin-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxamide and N-(4-(4-Amino-7-(1-isobutyrylpiperidin-4-yl)pyrrolo[1,2-f][1,2,4]triazin-5-yl)phenyl)-1-isopropyl-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxamide, which are useful as inhibitors of TAM kinases, as well as processes and intermediates related thereto.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.