Red blood cell targeted factor VIII and method of using the same
US11104718B2 · kind B2 · utility
0Cited by
3References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 14, 2017 |
| Grant date | Aug 31, 2021 |
| Priority date | — |
| Expiry date | Apr 13, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/50
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Targeted Factor VIII molecules comprising a Factor VIII linked with at least one domain that specifically binds to a membrane protein on a red blood cell is provided. The disclosed targeted coagulation factors prolong their duration of action and thus, are an improvement for the treatment of hematological diseases such as hemophilia A.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.