Ornithine transcarbamylase coding polyribonucleotides and formulations thereof

US11104887B2 · kind B2 · utility

Assignee

• ethris GmbH · DE

Inventors

• Carsten Rudolph · Krailling, DE
• Rebekka Kubisch-Dohmen · Munich, DE
• Manish Kumar Aneja · Munich, DE
• Johannes Geiger · Munich, DE
• Marino Schuhmacher · Birkenfeld, DE

Key dates

• Filing date: Dec 15, 2017
• Grant date: Aug 31, 2021
• Expiry date: Dec 15, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y201/03003
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

In certain aspects, the disclosure relates to compositions comprising modified Ornithine transcarbamylase (OTC) polyribonucleotides and methods of use.