Patent · US Active

Dinucleotides

US11110114B2 · kind B2 · utility

0Cited by

6References

36Claims

0Family size

Assignee

OXFORD UNIVERSITY INNOVATION LIMITED · GB

Inventors

Tom Brown · West Chester, US
Afaf Helmy El-Sagheer · Southampton, GB
Pawan Kumar · Norwalk, US

Key dates

Filing date	Jul 17, 2018
Grant date	Sep 7, 2021
Priority date	—
Expiry date	Jul 27, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07H19/16
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure relates to novel dinucleotides comprising at least two locked nucleosides, one of which is directly attached to the 3′ end of the triazole linker moiety and the other of which is directly linked to the 5′ end of the triazole linker moiety and that are useful for the preparation of oligonucleotides. The disclosed dinucleotides may be used in gene therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.