Tetrahydroquinoline compositions as BET bromodomain inhibitors
US11111229B2 · kind B2 · utility
3Cited by
93References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 28, 2020 |
| Grant date | Sep 7, 2021 |
| Priority date | — |
| Expiry date | Jan 28, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R1, R2, R5, and R8 are as described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.