Mass spectrometric data processing device for qualitative analysis
US11112391B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 25, 2015 |
| Grant date | Sep 7, 2021 |
| Priority date | — |
| Expiry date | Sep 30, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06F2218/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A degree of similarity in the peak pattern between a mass spectrum obtained for an unknown target substance in a sample and a mass spectrum of a known specific substance is calculated (S4). If the degree of similarity is within a range of 80-60% (“No” in S6), the ratio between the signal intensities at two mass-to-charge ratios characteristic of the specific substance is calculated and compared with a reference value (S7 and S8). If the intensity ratio exceeds the reference value, the target substance is likely to be the specific substance. Therefore, as in the case where the degree of similarity is equal to or higher than 80%, it is concluded that the specific substance is contained in the sample (S10). In advance of such a judgment, whether or not the sample has been certainly subjected to the mass spectrometric analysis is determined from a graph of the total ion current signal created from data collected by performing a measurement from a point in time before the sample is placed at a measurement position (S2 and S3). If no significant peak is present in the graph, it is concluded that a sample introduction error has occurred (S11). By such a method, a higher level of qualitati…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.