3,5-disubstituted pyrazoles useful as checkpoint kinase 1 (Chk1) inhibitors, and their preparations and applications
US11116767B2 · kind B2 · utility
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Key dates
| Filing date | Feb 4, 2016 |
| Grant date | Sep 14, 2021 |
| Priority date | — |
| Expiry date | Sep 6, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds of formula (I) which are potent inhibitors of Chk1 and have the structural formula below: wherein R1, R2, R3, R4, and R5 are as defined herein. Pharmaceutical compositions comprising the compounds, uses thereof and their preparation process are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.