Terpineol and preparation method and application thereof
US11117866B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 16, 2017 |
| Grant date | Sep 14, 2021 |
| Priority date | — |
| Expiry date | Apr 16, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/15
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses a terpinenol compound as well as its preparation method and application. The structure of such terpinenol compound is as shown in Formula (I) or (II). In Formula (I), R is independently selected from C12-C16 alkyl, —NR1R2, —SR3 or —OR4; R1, R2, R3 and R4 are independently selected from C1-C6 alkyl or —NO2; the C1-C6 alkyl can be substituted by OH; Alternatively, the R1 and R2 form a five-member ring or six-member ring in together with N used to link up them; the five-member or six-member ring may contain one O or C═O. As indicated by results of activity test, such terpinenol compound has satisfactory effect in prevention of asthma, inflammation and pulmonary artery hypertension, which also has high pharmaceutical significance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.