Non-hydrogen-bonding universal reader for DNA sequencing
US11119089B2 · kind B2 · utility
0Cited by
22References
13Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 21, 2017 |
| Grant date | Sep 14, 2021 |
| Priority date | — |
| Expiry date | May 10, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/50
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present disclosure provides apparatus and methods for determining the sequence of a nucleic acid. The apparatus comprises electrodes that form a tunnel gap through which the nucleic acid can pass. The electrodes comprise a reagent that is capable of selectively interacting with a nucleobase of the nucleic acid sequence. When the reagent interacts with a nucleobase, a detectable signal is produced and used to identify the nucleobase of the nucleic acid. Advantageously, the apparatus of this disclosure is specific to identifying nucleic acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.