Long-acting GLP-1R agonist as a therapy of neurological and neurodegenerative conditions

US11123405B2 · kind B2 · utility

Assignee

• THE JOHNS HOPKINS UNIVERSITY · US

Inventors

• Seulki Lee · Elkridge, US
• Ted M. Dawson · Baltimore, US
• Han Seok Ko · Baltimore, US
• Valina L. Dawson · Baltimore, US
• Seung Pil Yun · Timonium, US
• Magdalena Scully · Columbia, US

Key dates

• Filing date: Dec 22, 2016
• Grant date: Sep 21, 2021
• Expiry date: Dec 22, 2036

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/28
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to compositions and methods for treating neurodegenerative conditions using GLP-1r agonists. In certain embodiments, long-acting GLP-1r agonists have neuroprotective and disease modifying effects on the central nervous system.