System and method for removal of immune inhibitors from biological fluids
US11123467B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Oct 1, 2020 |
| Grant date | Sep 21, 2021 |
| Priority date | — |
| Expiry date | Oct 1, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/70578
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present system and method are useful for the removal of immune inhibitors such as soluble TNF receptors from the body fluid of cancer patients. In some embodiments, soluble TNF-Receptors 1 and 2 are selectively removed from plasma at 80% or more efficiency. In some embodiments, the system includes an immobilized capture ligand of a single chain TNFα. The system and method are useful for the treatment of different cancer types, stages and severity.
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