Patent · US Active

Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor I

US11124501B2 · kind B2 · utility

2Cited by
8References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 6, 2018
Grant dateSep 21, 2021
Priority date
Expiry dateDec 6, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/056
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to compounds of formula I as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 (HSF1). In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.