Patent · US Active

Chromatography resin, production and use thereof

US11124539B2 · kind B2 · utility

0Cited by

2References

11Claims

0Family size

Assignee

Cytiva BioProcess R&D AB · SE

Inventors

Johan William Ohman · Uppsala, SE
Mats Ander · Uppsala, SE
Therese Graner · Uppsala, SE
Anneli Jorsback · Uppsala, SE
Jinyu Zou · Uppsala, SE

Key dates

Filing date	Nov 14, 2017
Grant date	Sep 21, 2021
Priority date	—
Expiry date	Jan 29, 2038

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/95
WIPO fieldChemical engineering
WIPO sectorChemistry

Abstract

The present invention relates to the field of chromatography and more specifically to producing protein affinity chromatography resins comprising affinity ligands based on a N-terminal fragment of a split intein, such as DnaE from Nostoc punctiforme, as well as methods for using the same. The N-terminal fragments are produced in inclusion bodies in bacterial cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.