Methods for overcoming glutamine deprivation during mammalian cell culture
US11124760B2 · kind B2 · utility
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19References
18Claims
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Key dates
| Filing date | Mar 24, 2015 |
| Grant date | Sep 21, 2021 |
| Priority date | — |
| Expiry date | Aug 27, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2500/60
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention pertains to methods of producing polypeptide of interest in cell cultures lacking glutamine. The present invention further pertains to a method of producing a protein of interest in a large scale cell culture, comprising supplementing the cell culture with nucleic acid synthesis precursors and/or corticosteroids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.