Derivation of human microglia from pluripotent stem cells
US11124765B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Sep 21, 2018 |
| Grant date | Sep 21, 2021 |
| Priority date | — |
| Expiry date | Sep 21, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2513/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods for deriving human hematopoietic progenitors, primitive macrophages, and microglial cells from human pluripotent stem cells. In particular, provided herein are highly efficient and reproducible methods of obtaining human primitive macrophages and microglia from human pluripotent stem cells, where the primitive macrophages and microglia can be suitable for clinically relevant therapeutic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.