Methods and compositions for the inhibition of PIN1

US11129835B2 · kind B2 · utility

Assignees

• Beth Israel Deaconess Medical Center, Inc. · US
• THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER—NATIONAL INSTITUTES OF HEALTH · US

Inventors

• Kun Ping Lu · Newton, US
• Matthew B. Boxer · Point of Rocks, US
• Mindy Irene Emily Davis · Rockville, US
• Rajan Pragani · Rockville, US
• Min-Jui Richard Shen · Boyds, US
• Anton Simeonov · Rockville, US
• Shuo Wei · Sharon, US
• Xiao Zhen Zhou · Newton, US

Key dates

• Filing date: Sep 13, 2019
• Grant date: Sep 28, 2021
• Expiry date: Dec 24, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention features compositions and methods for inhibiting the Pin1 protein, and the treatment of disorders characterized by elevated Pin1 levels.