Inverse ugelstad particles

US11130833B2 · kind B2 · utility

Assignee

• Life Technologies AS · NO

Inventors

• Geir Fonnum · Lørenskog, NO
• Nils Pontus Lundberg · Strømmen, NO
• Muhammed Talha Gokmen · Lørenskog, NO
• Synne Larsen · Oslo, NO
• Wilhelm Glomm · Malvik, NO
• Heidi Johnsen · Trondheim, NO
• Ruth Schmid · Trondheim, NO
• Lars Kilaas · Trondheim, NO

Key dates

• Filing date: Oct 8, 2020
• Grant date: Sep 28, 2021
• Expiry date: Oct 8, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08F265/06
• WIPO field: Macromolecular chemistry, polymers
• WIPO sector: Chemistry

Abstract

This invention relates to monodisperse cross-linked hydrogel polymer particles comprising a polymer formed from (a) a hydrophilic vinylic monomer; and (b) a crosslinker comprising at least two vinyl groups. The invention also relates to monodisperse seed particles with a Z-average diameter of from 100 nm to 1500 nm that comprise a plurality of non-crosslinked oligomers of poly N,N-dimethylacrylamide. Also provided are methods of forming the monodisperse cross-linked hydrogel polymer particles and monodisperse seed particles.