Recombinant strain for producing L-lactic acid
US11130973B1 · kind B1 · utility
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Key dates
| Filing date | Dec 29, 2020 |
| Grant date | Sep 28, 2021 |
| Priority date | — |
| Expiry date | Dec 29, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y101/01028
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure relates to the technical fields of genetic engineering and microbial fermentation, and discloses a recombinant strain for producing L-lactic acid, wherein the recombinant strain is obtained by genetically modifying a starting strain, the activity of D-lactate dehydrogenase of the recombinant strain is weakened or inactivated, and the activity of L-lactate dehydrogenase is enhanced, as compared with the starting strain. The present invention can significantly improve the fermentation effect, the yield of the L-lactic acid and the optical purity of the product L-lactic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.