Simultaneous determination of aneuploidy and fetal fraction
US11130995B2 · kind B2 · utility
48Cited by
14References
17Claims
0Family size
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Key dates
| Filing date | Jul 31, 2017 |
| Grant date | Sep 28, 2021 |
| Priority date | — |
| Expiry date | Jul 31, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/112
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides compositions and methods for simultaneously determining the presence or absence of fetal aneuploidy and the relative amount of fetal nucleic acids in a sample obtained from a pregnant female. The method encompasses the use of sequencing technologies and exploits the occurrence of polymorphisms to provide a streamlined noninvasive process applicable to the practice of prenatal diagnostics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.