Method for preparing composition comprising a cationic oil-in-water emulsion
US11135287B2 · kind B2 · utility
22Cited by
15References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 7, 2019 |
| Grant date | Oct 5, 2021 |
| Priority date | — |
| Expiry date | May 22, 2039 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention generally relates to cationic oil-in-water emulsions that can be used to deliver negatively charged molecules, such as an RNA molecule. The emulsion particles comprise an oil core and a cationic lipid. The cationic lipid can interact with the negatively charged molecule thereby anchoring the molecule to the emulsion particles. The cationic emulsions described herein are particularly suitable for delivering nucleic acid molecules (such as an RNA molecule encoding an antigen) to cells and formulating nucleic acid-based vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.