Automated radiopharmaceutical production and quality control system
US11135321B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 10, 2015 |
| Grant date | Oct 5, 2021 |
| Priority date | — |
| Expiry date | Aug 16, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/8872
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An automated radiopharmaceutical production and quality control system includes a particle accelerator, a radiopharmaceutical micro-synthesis subsystem, and quality control subsystem. The micro-accelerator of the improved biomarker generator is optimized for producing radioisotopes useful in synthesizing radiopharmaceuticals in quantities on the order of multiple unit doses, allowing for significant reductions in size, power requirements, and weight when compared to conventional radiopharmaceutical cyclotrons. The radiopharmaceutical micro-synthesis subsystem encompasses a small volume chemical synthesis system comprising a microreactor and/or a microfluidic chip and optimized for synthesizing the radiopharmaceutical in small quantities, allowing for significant reductions in processing time and in the quantity of radioisotope required. The automated quality control subsystem is used to test the composition and characteristics of the radiopharmaceutical to ensure that it is safe to inject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.