Method to produce an immunoglobulin preparation with improved yield

US11136350B2 · kind B2 · utility

Assignee

• Takeda Pharmaceutical Company Limited · JP

Inventors

• Leopold Bruckschwaiger · Wien, AT
• Sonja Svatos · Ybbs an der Donau, AT
• Julia Nuernberger · Wien, AT
• Wolfgang Teschner · Wien, AT
• Harald Arno Butterweck · Wien, AT
• Hans-Peter Schwarz · Wien, AT
• Thomas Gundinger · Wien, AT
• Bernhard Koelbl · Achau, AT
• Reinhard Grausenburger · Wien, AT
• Azra Pljevljakovic · Wien, AT

Key dates

• Filing date: Nov 8, 2017
• Grant date: Oct 5, 2021
• Expiry date: Sep 12, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K1/34
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides improved methods for the manufacturing of IVIG products. These methods offer various advantages such as reduced loss of IgG during purification and improved quality of final products. In other aspects, the present invention provides aqueous and pharmaceutical compositions suitable for intravenous, subcutaneous, and/or intramuscular administration. In yet other embodiments, the present invention provides methods of treating a disease or condition comprising administration of an IgG composition provided herein.