Anti-C3 antibodies

US11136381B2 · kind B2 · utility

Assignee

• NGM Biopharmaceuticals, Inc. · US

Inventors

• Dana Yen Mei Duey · Burlingame, US
• Zhonghao Liu · Redwood City, US
• Jie Tang · Singapore, SG
• Yan Wang · San Diego, US
• Yiyuan Yin · Fremont, US
• Wenwu Zhai · Redwood City, US
• Jared Martin Higbee · San Francisco, US

Key dates

• Filing date: Apr 1, 2019
• Grant date: Oct 5, 2021
• Expiry date: Jul 14, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/94
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure provides binding agents, such as antibodies (including single chain variable fragments), that specifically bind complement component C3, including human C3, compositions comprising same, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising same.