Methods and compositions for modulaton of transforming growth factor beta-regulated functions
US11136383B2 · kind B2 · utility
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Key dates
| Filing date | Oct 25, 2017 |
| Grant date | Oct 5, 2021 |
| Priority date | — |
| Expiry date | Nov 25, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/33
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are compositions and methods for modulating the activity of TGF-β. More particularly, compositions and methods for modulating the release of active TGF-β from an LRRC33-TGF-β prodomain-TGF-β ternary complex are provided, as are and methods of treatment based upon such modulation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.