Method for production of reprogrammed cell using chromosomally unintegrated virus vector
US11136594B2 · kind B2 · utility
2Cited by
2References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 8, 2016 |
| Grant date | Oct 5, 2021 |
| Priority date | — |
| Expiry date | Mar 8, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/18843
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An objective of the present invention is to provide vectors for conveniently and efficiently producing ES-like cells in which foreign genes are not integrated into the chromosome. The present inventors discovered methods for producing ES-like cells from somatic cells using chromosomally non-integrating viral vectors. Since no foreign gene is integrated into the chromosome of the produced ES-like cells, they are advantageous in tests and research, and immunological rejection and ethical problems can be avoided in disease treatments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.