Patent · US Active

Gene expression signatures predictive of subject response to a multi-kinase inhibitor and methods of using the same

US11136625B2 · kind B2 · utility

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6Claims

0Family size

Assignee

CROWN BIOSCIENCE, INC. (TAICANG) · CN

Inventors

Sheng Guo · Durham, US
Daiwei Chen · Beijing, CN
Juan Zhang · San Diego, US
Jie Cai · Oceanside, US
Henry Qixiang Li · Russell, CA

Key dates

Filing date	Aug 28, 2014
Grant date	Oct 5, 2021
Priority date	—
Expiry date	Aug 28, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/158
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Gene expression signature predictive of cancer patient response to multi-kinase inhibitor is disclosed. Also disclosed are methods predicting the efficacy of the multi-kinase inhibitor for treating cancer in a patient. Also disclosed are methods for distinguishing responders from non-responders to a multi-kinase inhibitor in treating cancer. Also disclosed are methods for treating a cancer patient with a multi-kinase inhibitor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.