Systems and methods for rapid wide field illumination scanning for in vivo small animal fluorescence tomographic imaging
US11141064B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 19, 2017 |
| Grant date | Oct 12, 2021 |
| Priority date | — |
| Expiry date | Apr 3, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2201/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Presented herein are systems and methods for tomographic imaging that provide for rapid illumination of multiple excitation locations across a large field of view by one or more beams of excitation light from one or more excitation sources. The approaches described herein utilize a galvanometer optical scanner to scan a beam of excitation light through a plurality of locations across a scan region corresponding to the field of view to be imaged. In certain embodiments, the systems and methods described herein utilize beams of excitation light with specifically tailored shapes to maintain small spot sizes across the large scan region. The ability to scan over a large region while still maintaining small spot sizes provided by the approaches described herein allows for accurate, high-resolution tomographic imaging of large or multiple subjects, thereby expanding the capabilities of tomographic imaging systems.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.