Nanoemulsions comprising glycerol in aqueous phase
US11141362B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jan 4, 2018 |
| Grant date | Oct 12, 2021 |
| Priority date | — |
| Expiry date | Jan 4, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/805
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel oil-in-water nanoemulsions. The oil phase contains oil selected from the group consisting of triglyceride oil and/or petrolatum as well as C8 to C18 fatty acid; and the aqueous phase contains specific N-acyl derivatives having specific counterions of amino acid salt as emulsifier, glycerol, and water. When (i) there is defined ratio of glycerol to water; (ii) specific counterion for amino acid surfactant and (iii) fatty acid in oil phase. Nanoemulsions are processed in a one-step process yielding droplets of size 20 to 400 nm. In one embodiment, droplets of size 20 to 400 nm can be made using rotor-stator device (in one-step process) and in the absence of pressure based homogenizer. This saves in energy and cost. Compositions prepared according to this processes are also contemplated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.