Patent · US Active

Compositions comprising biodegradable copolymers for prolonged local release of an antibiotic

US11141488B2 · kind B2 · utility

0Cited by

21References

21Claims

0Family size

Assignee

DEXCEL PHARMA TECHNOLOGIES LTD. · IL

Inventors

Abraham J. Domb · Baltimore, US
Michael Grishko · Nesher, IL
Ezra Hanuka · Nesher, IL
Ron SCHLINGER · Haifa, IL
Tal Hagigit · Kalanswa, IL

Key dates

Filing date	Mar 29, 2017
Grant date	Oct 12, 2021
Priority date	—
Expiry date	Jul 18, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08G63/06
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A depot system containing at least one antibiotic and a biodegradable poly(ester-anhydride) of ricinoleic acid (RA) and sebacic acid (SA) having alternating or semi-alternating ester and anhydride bonds is provided. The system provides prolonged local release of the antibiotic at the site of injection while maintaining the systemic antibiotic levels at sub-therapeutic concentrations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.