Soft neural electrode based on three-dimensional porous graphene foam material and use of three-dimensional porous graphene foam material to prepare bone defect filler

US11145850B2 · kind B2 · utility

Assignee

• Soochow University · CN

Inventors

• Judong Luo · Suzhou, CN
• Qi Zhang · Mississauga, CA
• Yuyou Qiu · Suzhou, CN
• Shuyu Zhang · Suzhou, CN
• Qin SONG · Suzhou, CN
• Guangyu Tang · Suzhou, CN
• Jianping Cao · Suzhou, CN
• Hua Jiang · Shanghai, CN

Key dates

• Filing date: May 10, 2017
• Grant date: Oct 12, 2021
• Expiry date: Jul 8, 2037

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02E60/10
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

The invention provides a neural electrode, including a current generation device, a first and a second electrode. The current generation device is connected to the first and second electrodes through a conductive metal wire respectively. At least one of the first and second electrodes is a graphene electrode. The graphene electrode has soft texture and desirable stability to tolerate the repeated pressing and folding treatment, very high charge injection efficiency, and desirable in vivo stability, and is configured to electrically stimulate tissues and organs such as hearts and nerves to promote electrical stimulation and repair of neurons, to further promote regeneration of neural functions. The invention further provides use of a mineralized three-dimensional porous graphene foam material to prepare a bone defect filler. The bone defect filler has desirable biological compatibility, promotes cell proliferation, and accelerates and induces osteogenic differentiation of bone marrow mesenchymal stem cells.