Patent · US Active

Pharmaceutical composition containing DUSP1 inhibitor

US11147807B2 · kind B2 · utility

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6Claims
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Key dates

Filing dateFeb 28, 2018
Grant dateOct 19, 2021
Priority date
Expiry dateJun 5, 2038

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a pharmaceutical composition comprising a DUSP1 inhibitor. The pharmaceutical composition comprising the DUSP1 inhibitor according to the present invention can solve the problems of inhibitors that target the active site because it inhibits DUSP1 by an allosteric inhibitory mechanism, and is effective for preventing or treating diseases involving DUSP1 enzymes, for example, a cancer such as a liver cancer, a breast cancer and a pancreatic cancer, a hepatitis C, and a depression. In particular, the DUSP1 inhibitor according to the present invention is very effective in treating a depression because it directly acts on neuronal growth.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.